teduglutide


SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)N
InChIKey CILIXQOJUNDIDU-ASQIGDHWSA-N
Sequence HGDGSFSDEMNTILDNLAARDFINWLIQTKITD

Chemical properties

Hydrogen bond acceptors 53
Hydrogen bond donors 55
Rotatable bonds 125
Molecular weight (Da) 3749.8

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-2 GLP2R Rat Glucagon B1 pEC50 10.1 10.1 10.1 ChEMBL
GLP-2 GLP2R Human Glucagon B1 pEC50 8.0 8.0 8.0 Drug Central
GLP-2 GLP2R Rat Glucagon B1 pEC50 8.0 8.0 8.0 Drug Central
GLP-2 GLP2R Human Glucagon B1 pEC50 10.05 10.52 11.0 ChEMBL
GLP-2 GLP2R Human Glucagon B1 pEC50 10.7 10.7 10.7 Guide to Pharmacology