JNJ-42396302


SMILES COCCc1ccc(-c2c(C)nc3c(N4CCOCC4)ccnn23)cn1
InChIKey BPLVDYJDAVYLRQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.06 5.06 5.06 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.65 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.66 5.68 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database