CHEMBL2181188


SMILES CCCN1CCC(COc2nc3c(Cl)cccc3c3ccccc23)CC1
InChIKey GGQFEMQQQLOYIH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.05 5.05 5.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 6.6 6.6 6.6 ChEMBL