CHEMBL218404


SMILES C[C@H]1CN2CCN(C(=O)c3ccccc3)C[C@H]2C[C@@]1(C)c1cccc(O)c1
InChIKey CJMYGZTZUKJGEF-XTQVGHSUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.6 7.6 7.6 ChEMBL
κ OPRK Human Opioid A pKi 6.72 6.73 6.75 ChEMBL
μ OPRM Human Opioid A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 7.85 7.85 7.85 ChEMBL
κ OPRK Human Opioid A pIC50 7.3 7.3 7.3 ChEMBL
μ OPRM Human Opioid A pIC50 7.68 8.18 8.68 ChEMBL