CHEMBL219318


SMILES C[C@H]1CN2CCN(Cc3ccccc3Cl)C[C@H]2C[C@@]1(C)c1cccc(O)c1
InChIKey NZLFDRJFUHYJKI-XTQVGHSUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.24 7.24 7.24 ChEMBL
κ OPRK Human Opioid A pKi 7.8 7.8 7.8 ChEMBL
μ OPRM Human Opioid A pKi 9.33 9.33 9.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 6.72 6.72 6.72 ChEMBL
κ OPRK Human Opioid A pIC50 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pIC50 8.74 8.74 8.74 ChEMBL