CHEMBL219734


SMILES O=C1c2c(OC(F)(F)F)cccc2C2CNCCN12
InChIKey QCDPKPGZFATVMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 272.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.3 6.3 6.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.58 7.58 7.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.06 7.06 7.06 ChEMBL