CHEMBL220596


SMILES Cc1cc(C)c2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC4(C(=O)N5CCN(C(=O)C[C@@H](N)CCCN(C)C)CC5)CCCC4)c3Cl)c2n1
InChIKey PWTMLUZFONSYFK-SANMLTNESA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 746.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Guinea pig Bradykinin A pKd 10.4 10.4 10.4 ChEMBL
B2 BKRB2 Human Bradykinin A pKi 9.2 9.2 9.2 ChEMBL
B2 BKRB2 Human Bradykinin A pKd 8.8 8.8 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database