CHEMBL2208349


SMILES CC1C2Cc3ccc(C(=O)NCCc4ccc(-c5ccccc5O)cc4)cc3C1(C)CCN2CC1CC1
InChIKey XDPGTKZCXIUYTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 494.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.62 9.62 9.62 ChEMBL
κ OPRK Human Opioid A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.8 9.8 9.8 ChEMBL
κ OPRK Human Opioid A pEC50 10.07 10.07 10.07 ChEMBL
μ OPRM Human Opioid A pIC50 7.19 7.19 7.19 ChEMBL
μ OPRM Human Opioid A pEC50 8.82 8.82 8.82 ChEMBL