CHEMBL2208351


SMILES CC1C2Cc3ccc(C(=O)NCCc4ccc(-c5ccc6c(c5)OCO6)cc4)cc3C1(C)CCN2CC1CC1
InChIKey NFVWPZJBRDAYII-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 522.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
κ OPRK Human Opioid A pKi 9.14 9.14 9.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.1 9.1 9.1 ChEMBL
κ OPRK Human Opioid A pEC50 9.47 9.47 9.47 ChEMBL
μ OPRM Human Opioid A pIC50 7.96 7.96 7.96 ChEMBL
μ OPRM Human Opioid A pEC50 9.82 9.82 9.82 ChEMBL