CHEMBL221129


SMILES CCCc1c(C(=O)NCCCCCN2CCN(c3ccccc3OC)CC2)nnn1Cc1ccccc1Br
InChIKey FLQHAMHLQRATPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 582.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.13 8.13 8.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.28 8.66 9.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database