TRV027


SMILES CNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)O)C)Cc1[nH]cnc1)[C@H](CC)C)Cc1ccc(cc1)O)C(C)C)CCCN=C(N)N
InChIKey XIEWFECSPPTVQN-KMIMAYJXSA-N
Sequence XRVYIHPA

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 26
Molecular weight (Da) 925.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pKd 7.72 7.72 7.72 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRA Rat Angiotensin A pEC50 7.8 7.8 7.8 ChEMBL
AT1 AGTR1 Human Angiotensin A pEC50 7.77 7.77 7.77 ChEMBL