CHEMBL2220978


SMILES COc1ccccc1N1CCN(CCc2ccc3c(c2)OCO3)CC1
InChIKey ZFLJBXISNFUYBH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.28 8.28 8.28 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.9 8.9 8.9 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.46 8.46 8.46 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 8.26 8.26 8.26 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 9.85 9.85 9.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Rat Adrenoceptors A pIC50 8.22 8.22 8.22 ChEMBL
α1A ADA1A Rat Adrenoceptors A pIC50 9.57 9.57 9.57 ChEMBL