CHEMBL222715


SMILES CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1
InChIKey JDFLTRXXHVSTHR-OCSRFSMESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 359.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Mouse Prostanoid A pKi 6.47 6.47 6.47 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 8.77 8.77 8.77 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 7.07 7.07 7.07 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 6.89 6.9 6.92 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 4.96 4.96 4.96 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 8.54 8.62 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Rat Prostanoid A pEC50 5.75 5.75 5.75 ChEMBL
EP4 PE2R4 Rat Prostanoid A pEC50 8.51 8.51 8.51 ChEMBL
EP2 PE2R2 Human Prostanoid A pEC50 7.82 7.82 7.82 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.96 9.33 10.7 ChEMBL