CHEMBL22650


SMILES C=CCN1CC[C@@H](N(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)[C@@H](C)C1
InChIKey DZIVFTSZIVQCKX-SQJMNOBHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 405.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 5.43 5.58 5.84 ChEMBL
δ OPRD Mouse Opioid A pKi 6.86 6.86 6.86 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.84 5.84 5.84 ChEMBL
μ OPRM Rat Opioid A pKi 5.58 5.69 5.92 ChEMBL
κ OPRK Human Opioid A pKi 5.43 5.43 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database