CHEMBL232285


SMILES CCS(=O)(=O)N1CCN(Cc2ccccc2C2(O)CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)CC1
InChIKey RGOFVQWZORFHTD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 601.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.05 9.05 9.05 ChEMBL
δ OPRD Human Opioid A pKi 5.8 5.8 5.8 ChEMBL
κ OPRK Human Opioid A pKi 6.84 6.84 6.84 ChEMBL
μ OPRM Human Opioid A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database