CCR2-RA-[R]


SMILES Clc1ccc(c(c1)F)N1[C@H](C2CCCCC2)C(=C(C1=O)O)C(=O)C
InChIKey VQNLJXWZGVRLBA-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 5T1A

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Human Chemokine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Human Chemokine A pIC50 5.3 5.3 5.3 Guide to Pharmacology
CCR2 CCR2 Human Chemokine A pIC50 6.77 7.65 8.0 ChEMBL
CCR5 CCR5 Human Chemokine A pIC50 6.15 6.15 6.15 ChEMBL