CHEMBL2364961


SMILES O=C1N[C@@H]2CNC[C@H]2c2cccc(C(F)(F)F)c21
InChIKey PKCRBWNXYKXDQR-IONNQARKSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 256.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.21 7.21 7.21 ChEMBL