CHEMBL2365635


SMILES CC(C)CN1CC[C@H]2c3c(ccc(O)c3O)C[C@@H]1[C@]2(O)CCCN(C)C(=O)/C=C/c1ccoc1
InChIKey VGWSWRCANUNAIT-RQLMBIGASA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 468.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 7.33 7.33 7.33 ChEMBL
δ OPRD Mouse Opioid A pKi 6.29 6.29 6.29 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.23 9.23 9.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.09 8.09 8.09 ChEMBL