CHEMBL2365705


SMILES O=C1N[C@H]2CNC[C@@H]2c2ccc(Cl)c(Cl)c21
InChIKey UFIHFWYXISGIHY-SVRRBLITSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 256.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.32 7.32 7.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.38 6.38 6.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.48 8.48 8.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.89 6.89 6.89 ChEMBL