CHEMBL236610


SMILES CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1Cl
InChIKey JVCJWEYSNNCGKX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST5 SSR5 Human Somatostatin A pKi 6.95 6.95 6.95 ChEMBL
H1 HRH1 Human Histamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
H1 HRH1 Human Histamine A pKi 6.58 6.58 6.58 PDSP Ki database
SST2 SSR2 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
SST3 SSR3 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 PDSP Ki database
SST4 SSR4 Human Somatostatin A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database