CHEMBL236663


SMILES Cc1cccc(C)c1Cc1[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C
InChIKey PFRMPRUILAXAIG-VWLOTQADSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 10
Molecular weight (Da) 490.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pKd 6.61 6.61 6.61 ChEMBL
δ OPRD Human Opioid A pKi 8.28 8.28 8.28 ChEMBL
μ OPRM Human Opioid A pKi 9.18 9.18 9.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database