CHEMBL2367916


SMILES C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1
InChIKey FUMBLBJFVJXVBV-VWMXVWASSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 346.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.28 8.28 8.28 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.57 8.8 9.27 ChEMBL
δ OPRD Human Opioid A pKi 6.57 7.72 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.42 8.42 8.42 ChEMBL
μ OPRM Human Opioid A pEC50 7.82 7.82 7.82 ChEMBL