CHEMBL237295


SMILES NC(=O)c1ccc(Oc2ccc(CCN3CCc4ccccc4C3)cc2)nc1
InChIKey RAFLIAKPWNTXKX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.84 6.84 6.84 ChEMBL
κ OPRK Human Opioid A pKi 6.73 6.73 6.73 ChEMBL
δ OPRD Human Opioid A pKi 6.84 6.84 6.84 PDSP Ki database
κ OPRK Human Opioid A pKi 6.73 6.73 6.73 PDSP Ki database
μ OPRM Human Opioid A pKi 8.3 8.3 8.3 PDSP Ki database
μ OPRM Human Opioid A pKi 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database