CHEMBL2375157


SMILES Cc1cc(O)cc(C)c1C[C@@H](C)CN1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1nc2ccccc2[nH]1
InChIKey NWCLUPOGVWVFRT-OLILMLBXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 539.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pKd 9.0 9.0 9.0 ChEMBL
μ OPRM Rat Opioid A pKi 7.69 7.69 7.69 ChEMBL
δ OPRD Human Opioid A pKi 10.46 10.46 10.46 ChEMBL
μ OPRM Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 9.89 9.89 9.89 ChEMBL