CHEMBL2387260


SMILES Cc1cc(=O)oc2cc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12
InChIKey NAIAJYNMEREGMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.71 7.71 7.71 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.46 8.46 8.46 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.31 8.31 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database