CHEMBL2392183


SMILES COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cn1
InChIKey FFRLOXKAKNBOMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 418.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pKi 7.59 7.59 7.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Mouse A orphans A pEC50 5.3 5.3 5.3 ChEMBL
GPR35 Q33BM1 Rat A orphans A pEC50 6.0 6.0 6.0 ChEMBL
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pIC50 5.21 5.21 5.21 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 7.52 7.52 7.52 ChEMBL