CHEMBL2401938


SMILES COc1ccc2c(=O)c3cc(CN4CCN(c5ccccc5OC)CC4)ccc3oc2c1
InChIKey TYGHMVYMNAHTMO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.94 5.94 5.94 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.87 4.87 4.87 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database