CHEMBL2414991


SMILES CN1CCc2cc(O)c(O)c3c2C1Cc1ccccc1-3
InChIKey SYKWSIUDXOQIDR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 267.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.35 7.38 7.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.08 6.08 6.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.47 6.78 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 4.99 4.99 4.99 ChEMBL