CHEMBL244161


SMILES CNc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey MOARTSKNGANIHC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 434.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Guinea pig 5-Hydroxytryptamine A pKd 7.7 7.7 7.7 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.59 7.59 7.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.97 6.97 6.97 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database