CHEMBL2441619


SMILES Cc1ccc2nc(C(F)(F)F)cc(N3CCNCC3)c2c1
InChIKey ZKHOZLXKYFBVMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 295.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.4 6.4 6.4 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.92 5.92 5.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKd 7.41 7.58 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database