CHEMBL2443007


SMILES COc1ccccc1N1CCN(Cc2cn(-c3ccc(OCCCOCCF)cc3)nn2)CC1
InChIKey GVZVJCKGJVWISH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 469.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.58 6.58 6.58 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.44 5.44 5.44 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.54 5.54 5.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.11 6.24 6.36 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database