CHEMBL2443010


SMILES COc1ccccc1N1CCN(Cc2cn(CCOCCF)nn2)CC1
InChIKey FLNGBOIVGQBOBU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.68 6.68 6.68 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.68 4.68 4.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.77 5.77 5.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 5.96 6.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database