CHEMBL244577


SMILES O=C(CCCCCN1CCN(c2ccccc2F)CC1)NC1CCCc2ccccc21
InChIKey GJXLROXNFUKMEK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.53 6.53 6.53 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database