CHEMBL244792


SMILES O=C(CCCCCN1CCN(c2cccc[n+]2[O-])CC1)NC1CCCc2ccccc21
InChIKey UKQVZMCEYHZTPP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 422.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.09 5.09 5.09 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.1 5.1 5.1 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database