CHEMBL111184


SMILES COc1cccc2c1N1CCN(C)C[C@@H]1c1ccccc1C2
InChIKey GZXNMNCAWGIAAW-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 294.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 9.8 9.8 9.8 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.34 6.34 6.34 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database