CHEMBL250993


SMILES C[C@H]1C2Cc3ccc(C(=O)NCCc4cccc(Br)c4)cc3[C@@]1(C)CCN2CC1CC1
InChIKey CFCYDKRYHOSVHZ-CGOBKJRRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 480.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.46 8.46 8.46 ChEMBL
κ OPRK Human Opioid A pKi 10.2 10.2 10.2 ChEMBL
μ OPRM Human Opioid A pKi 9.46 9.46 9.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.85 7.85 7.85 ChEMBL
κ OPRK Human Opioid A pEC50 8.34 8.34 8.34 ChEMBL
μ OPRM Human Opioid A pIC50 6.64 6.64 6.64 ChEMBL
μ OPRM Human Opioid A pEC50 8.25 8.25 8.25 ChEMBL