CHEMBL251599


SMILES Cc1nc(-c2ccc(OCCNC[C@H](O)c3cccnc3)cc2)cs1
InChIKey MPBSKGHZYFSSQJ-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 7.0 7.0 7.0 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Rat Adrenoceptors A pEC50 7.89 7.89 7.89 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 6.77 6.77 6.77 ChEMBL