CHEMBL253096


SMILES CC1(c2cccc(OCc3ccccc3)c2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O
InChIKey QASCBWTWFDWZJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 425.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database