CHEMBL256075


SMILES COc1cc2c(cc1O)C[C@H]1c3c(c(I)c(O)c(OC)c3-2)CCN1C
InChIKey YCBIBKGMUXWRRT-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 453.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 8.7 8.7 8.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 8.52 8.52 8.52 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.02 7.02 7.02 ChEMBL