colchicine


SMILES COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC
InChIKey IAKHMKGGTNLKSZ-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 399.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TAS2R4 TA2R4 Human Taste 2 T2 pEC50 2.99 2.99 2.99 Guide to Pharmacology
TAS2R46 T2R46 Human Taste 2 T2 pEC50 2.8 2.8 2.8 Guide to Pharmacology
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 6.05 6.05 6.05 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.6 5.6 5.6 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.8 5.25 5.7 ChEMBL