CHEMBL26533


SMILES COc1ccccc1N1CCN(CCCCNC(=O)C23C[C@H]4C[C@@H](C2)C[C@@H](C3)C4)CC1
InChIKey PRZPXKIXNNNNCD-DJICYOIISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 425.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Bovine Dopamine A pKi 8.57 8.57 8.57 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKd 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database