compound 11 [PMID: 15261275]


SMILES O=C(Nc1ccc(cc1Cl)Br)N[C@H]1COC(O[C@H]1c1ccccc1)(C)C
InChIKey HHNAHVCOGFTMSQ-IRXDYDNUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 438.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX2 OX2R Human Orexin A pKi 8.3 8.3 8.3 Guide to Pharmacology
OX1 OX1R Human Orexin A pKi 8.2 8.2 8.2 ChEMBL
OX1 OX1R Human Orexin A pKi 5.3 5.3 5.3 Guide to Pharmacology
OX2 OX2R Human Orexin A pKi 8.2 8.2 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database