CHEMBL113471


SMILES COc1c(C(=O)NCC[C@@H]2CCN(Cc3ccccc3)C2)cc(Br)c2ccccc12
InChIKey RJZYRNTXYJEPMD-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 466.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.68 5.72 5.77 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.21 6.25 6.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.12 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.55 5.64 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database