(S,R)-IFENPRODIL


SMILES C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1
InChIKey UYNVMODNBIQBMV-IIBYNOLFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.57 7.57 7.57 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pIC50 7.0 7.0 7.0 ChEMBL