CHEMBL277362


SMILES CNCCc1c[nH]c2ccc(O)cc12
InChIKey ASUSBMNYRHGZIG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 190.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT2A

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 7.35 7.35 7.35 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.3 8.3 8.31 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPS NPSR1 Human Neuropeptide S A Potency 6.4 6.4 6.4 ChEMBL