CHEMBL277530


SMILES COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(NC(=O)Cc5ccc(Cl)cc5)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey FFDBZKOGLUZBID-FQYQUSJJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 506.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.29 7.29 7.29 ChEMBL
κ OPRK Human Opioid A pKi 8.59 8.59 8.59 ChEMBL
μ OPRM Human Opioid A pKi 8.58 8.58 8.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 7.05 7.05 7.05 ChEMBL
κ OPRK Human Opioid A pIC50 8.04 8.04 8.04 ChEMBL
μ OPRM Human Opioid A pIC50 8.05 8.05 8.05 ChEMBL