PHENINDAMINE


SMILES CN1CCC2=C(C1)C(c1ccccc1)c1ccccc12
InChIKey ISFHAYSTHMVOJR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 261.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKi 8.2 8.2 8.2 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 8.8 8.8 8.8 ChEMBL
H1 HRH1 Rat Histamine A pKi 7.7 7.7 7.7 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKd 8.06 8.06 8.06 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pIC50 7.44 7.44 7.44 ChEMBL