CHEMBL280220


SMILES CCCc1c(C(=O)OCC)c2c3c(ccc2n1C)OC1c2ccc(SC)cc2CCN1C3
InChIKey GCLKZSBEVYSDDQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.77 5.77 5.77 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.7 8.7 8.7 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.64 6.64 6.64 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.42 5.42 5.42 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.48 5.48 5.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database