CHEMBL114379


SMILES Oc1nc2ccccc2n1C1CCN(Cc2cc3c(cc2Cl)OCO3)CC1
InChIKey QETCNYZNLBVXLI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 385.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 7.42 7.42 7.42 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pIC50 5.72 5.72 5.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.12 6.12 6.12 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.29 6.29 6.29 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.72 5.72 5.72 ChEMBL
δ OPRD Human Opioid A pIC50 7.43 7.43 7.43 ChEMBL
κ OPRK Human Opioid A pIC50 8.77 8.77 8.77 ChEMBL
μ OPRM Human Opioid A pIC50 8.92 8.92 8.92 ChEMBL