CHEMBL28313


SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1
InChIKey ZRWGXXAMGVLDQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 337.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 8.55 8.55 8.55 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.77 7.29 7.82 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.16 6.16 6.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database